Neurourology & Female Urology

Steven P. Petrou
2008 International Brazilian Journal of Urology  
with an intravesical therapeutic solution of lidocaine, heparin, and sodium bicarbonate. active and were treated with an intravesical therapeutic solution. All patients provided their medical history, underwent a physical examination, and completed the Pelvic Pain Urgency Frequency symptom scale, voiding diary, and the pain domain (questions 17 to 19) of the Female Sexual Function Index before and after therapy. of Symptom scale. reported improvements of greater than 50% on the Patient
more » ... he Patient Objective Rating of Improvement of Symptom with bladder tenderness only versus the 7 with multiple tender locations on the vaginal examination, 11 (85%) Conclusions: The results of this study have demonstrated that an intravesical therapeutic solution provides relief randomized, prospective trial is warranted. Editorial Comment The authors analyzed the rate of dyspareunia in a female patient population diagnosed with interstitial tion three times a week for three weeks in a row. The therapy seemed to have a certain level of durability in a much higher response rate if prior to treatment they were plagued with bladder tenderness only on physical examination as opposed to a diffusely painful vagina on digital palpation. This interesting paper highlights the association of sexual problems in patients with interstitial cystitis. It is heartening that those patients who had basically only bladder tenderness on vaginal palpation experienced an 85% resolution of their dyspareunia with this instillation therapy. The authors note that alkalinizing the lidocaine will allow it to have a greater penetration of bladder epithelium. Alkalinization of lidocaine has also been that the total solution instilled in the bladder was only 14 cc while the lidocaine gel instilled in the urethra to -
doi:10.1590/s1677-55382008000200022 fatcat:uomjf5pcanfdnfnix3td6pxxhe