A CLINICAL INVESTIGATION OF THE CARBONIC ACID IN THE ALVEOLAR AIR
Archives of Internal Medicine
have shown that the maintenance of a definite percentage of carbon dioxid in the alveolar air of the lungs and in the blood is of prime importance to the organism and is maintained by a definite physiological regulation. They have also shown that overventilation of the lungs by hyperpnea, which reduces the concentration of the CO2 in the alveolar air below normal, gives rise to a feeling of weakness and giddiness exactly like that of mountain sickness, and when pushed to extremes, also to
... emes, also to periodic breathing of the Cheyne-Stokes type. Yandell Henderson has produced a good deal of evidence to indicate that the clinical manifestations of surgical shock may be brought about by a condition of acapnia; and Porges, Leimd\l=o"\rferand Marcovici have found acapnia present in cases of acidosis and in certain cases of cardiac dyspnea. As the subject seemed to warrant further investigation from the clinical side, the following observations were made. We take great pleasure in expressing our thanks to Drs. Barker, Thayer, Halsted and Williams for the privilege of investigating cases in their respective services in the Johns Hopkins Hospital, as well as to the members of the house staff for their hearty cooperation.