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... suspected necrotic arachnidism. N Engl J Med 352:700-7 Tambourgi DV, Morgan BP, Goncalves-de-Andrade RM, Magnoli FC, van den Berg CW (2000) Loxosceles intermedia spider envenomation induces activation of an endogenous metalloproteinase, resulting in cleaving of glycophorins from the erythrocyte surface and facilitating complement-mediated lysis. Blood 95:683-91 Truett AP III, King LE Jr (1993) Sphingomyelinase D: a pathogenic agent produced by bacteria and arthropods. In: Sphingolipids: Regulation and Function of Metabolism, Advances in Lipid Research (Bell RM, Hannun YA, Merrill AH Jr, eds), Vol 26B, Academic Press: San Diego, 275-91 Van den Berg CW, Goncalves-de-Andrade RM, Magnoli FC, Marchbank KJ, Tambourgi DV (2002) Loxosceles spider venom induces metalloproteinases mediated cleavage of MCP/ CD46 and MHC I and induces protection again C-mediated lysis. Immunology 107:102-10