Microencapsulation by spray drying of Lannea microcarpa extract: Technological characteristics and antioxidant activity

Francesca Sansone, Teresa Mencherini, Patrizia Picerno, Tiziana Esposito, Pasquale Del Gaudio, Paola Russo, Giacomo Pepe, Maria R. Lauro, Rita P. Aquino
2014 Journal of Pharmacy & Pharmacognosy Research  
Context: A functional extract from Lannea microcarpa (Lm), possess interesting antioxidant and anti-inflammatory properties. However, the unprocessed dried extract occurs as sticky and low-water-soluble material showing critical properties for industrial applications. The unprocessed dried extract is not always enough stable to preserve its functional properties, also giving practical difficulties for the manufacturing. Aims: This research aimed to produce Lm extract microparticles with
more » ... ticles with enhanced functional stability and technological characteristics by spray-drying. Methods: Lm extract was microencapsulated by spray-drying using a sodium-carboxymethylcellulose (NaCMC) based matrix. Physicochemical and technological characteristics (determined by UV, HPLC, LLS, SEM, DSC, and in vitro dissolution tests), as well as antioxidant properties (DPPH-test) of the resulting powder (LmC) were examined. Results: The produced spray dried microparticles showed satisfying encapsulation efficiency, good functional stability and enhanced technological properties. The selected carrier and process conditions led to a stable and handling microencapsulated powder form with improved water dissolution rate. Moreover, the matrix was also able to preserve the antioxidant activity of the phenolic compounds-rich extract. Conclusions: The made-up powder resulted in a functional component that can be used with great potential in cosmetics, foods or nutraceutical products.
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