Chemical composition and biological screening of Capsella bursa-pastoris

Clara Grosso, Juliana Vinholes, Luís R. Silva, Paula Guedes de Pinho, Rui F. Gonçalves, Patrícia Valentão, Anna K. Jäger, Paula B. Andrade
2011 Revista Brasileira de Farmacognosia  
Capsella bursa-pastoris (L.) Medik. (Brassicaceae) is a wild herb with high nutritional value that can be eaten raw or cooked. A metabolomic study was performed with different extracts of its aerial parts that were tested concerning their antiradical, acetylcholinesterase inhibitory and antibacterial activities. Phenolic compounds were identified and quantified by HPLC-DAD, organic acids and amino acids were determined by HPLC-UV, while free fatty acids and sterols were analysed by GC-ITMS. The
more » ... sed by GC-ITMS. The vegetal material was rich in kaempferol-3-O-rutinoside (mean value 2247.09 mg/kg of dry plant), quinic acid (95628.00 mg/kg of dry plant), arginine (mean value of 1.18 mg/kg of dry plant), palmitic acid (284.48 mg/kg) and β-sitosterol (28%). The extracts presented a concentration-dependent antiradical activity (against DPPH • , O 2 •and LOO • ), being most effective against • NO (EC25 0.20 μg/mL). In addition, the extracts were also acetylcholinesterase inhibitors and antibacterial active, revealing that, besides the plant's good nutritional value, it presents important biological properties as well.
doi:10.1590/s0102-695x2011005000107 fatcat:m3dfsaandfaindx6suqxv63y3a