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Thermotolerant Cells Show an Attenuated Expression of Hsp70 after Heat Shock
Journal of Biological Chemistry
Expression of heat shock proteins (hsps) results in the protection of cells from subsequent stresses. However, hsps are also toxic when present within cells for a prolonged time period. Thus, the expression of hsps should be tightly regulated. In the present study, the expression of Hsp70 after heat shock was compared between thermotolerant cells, which contain a large concentration of Hsp70, and nonthermotolerant cells (naive). Accumulation of Hsp70, assessed by Western blotting, wasdoi:10.1074/jbc.274.17.12081 pmid:10207033 fatcat:fqe5whm665dyjod7wdyif4lx7u