The INO80 Complex Removes H2A.Z to Promote Presynaptic Filament Formation during Homologous Recombination

Claudio A. Lademann, Jörg Renkawitz, Boris Pfander, Stefan Jentsch
2017 Cell Reports  
Graphical Abstract Highlights d INO80-C has a dual function in both DNA end resection and Rad51 filament formation d The major substrate of INO80-C at DSBs is H2A.Z d H2A.Z inhibits Rad51 filament formation but not DNA end resection in the absence of INO80-C
doi:10.1016/j.celrep.2017.04.051 pmid:28514650 fatcat:4b7ck6je65c4tn2yjds46z55ka