High-carbohydrate and high-protein diets alter liver and brain insulin receptors in rats

P. Maćkowiak, D. Ładoń, L. Nogowski, K. Nowak
1993 Journal of Animal and Feed Sciences  
Insulin receptors of liver and brain plasma membranes were investigated in rats kept on standard (S), high-carbohydrate (HC) and high-protein (HP) diets. Both liver and brain show similar tendency to reduce number of high affinity receptors and their affinity to the hormone in rats fed a HP diet. After a HC diet the effects seem to be opposite. Animals show nearly the same number of receptors as in the control group but the affinity of insulin binding to liver -but not brain plasma membranes is enhanced.
doi:10.22358/jafs/69883/1993 fatcat:cwey7qb6preyriuqk6qjucfdpy