INTRODUCTION Review question / Objective: We aim to systematically review the effectiveness and safety of traditional Chinese medicine f u m i g a n t s f o r d i a b e t i c p e r i p h e r a l neuropathy. C o n d i t i o n b e i n g s t u d i e d : D i a b e t i c peripheral neuropathy is one of the most common complications of diabetes, and about half of diabetic patients will be affected. It can lead to foot infections and even severe consequences of amputation. Review question / Objective:

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... We aim to systematically review the effectiveness and safety of traditional Chinese medicine fumigants for diabetic peripheral neuropathy. Condition being studied: Diabetic peripheral neuropathy is one of the most common complications of diabetes, and about half of diabetic patients will be affected. It can lead to foot infections and even severe consequences of amputation. This is usually a heavy burden for the healthcare system and patients. However, there is no safe and effective clinical treatment for diabetic peripheral neuropathy. Clinical practice shows that traditional Chinese medicine fumigants can improve the symptoms of diabetic peripheral neuropathy and increase nerve conduction speed. The purpose of this study is to provide a high-quality comprehensive evaluation of the efficacy and safety of traditional Chinese medicine fumigants in the treatment of diabetic peripheral neuropathy.