Original Article The novel affiliation treatment for children with deprivation amblyopia after congenital cataract surgery

Lei Ye, Zeng-Renqing Dan, Ling Chen, Dong-Yi Qu, Lin-Hong Ye, Qi-Chen Yang, Nan Jiang, Qiong Zhou, Yi Shao
2017 Int J Clin Exp Med   unpublished
To compare the effect among different treatment for deprivation amblyopia after congenital cataract extraction and IOL implantation. Material/Methods: Totally 38 subjects diagnosed of deprivation amblyopia (aged from 5 a to 10 a) were divided into three groups and treated with different therapeutic methods: conventional treatment (group A), the video game treatment (group B), and combination of the video game and heat-sensitive moxibustion treatment (group C). After 60 days of above treatment,
more » ... ll cases received therapy with red light flicker, luster, and light brush for 120 days at home. In addition, visual acuity and visual evoked potentials (VEP) were measured in all cases at pre-therapy and 20 d, 40 d, 60 d, 180 d post-therapy during the period of treatment. Results: There was no significant difference in age, course and visual acuity in three groups (P>0.05). After 180 days of treatment the visual acuity of all case in three groups were higher than pre-therapy, and the best-corrected visual acuity (BCVA) of group B and group C were higher than group A at every time point (P<0.05). The BCVA was improved from baseline by an average of 0.87 lines in the group A, 3.00 lines in the group B and 6.06 lines in the group C. Comparing with before treatment, the latency of P100 of VEP elicited by reversing checkerboard with different spatial frequencies were shortened significantly in three groups at 180 d. In addition, the latency of P100 of VEP elicited in group C were shorter than other cases in group A and B (all P<0.05). Conclusions: Compared two conventional treatment, heat-sensitive moxibustion affiliation treatment is better therapeutic tool for deprivation amblyopia after congenital cataract extraction and IOL implantation, and it should be widely applied in clinical treatment.