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University of the Future: Re-Imagining Research and Higher Education
The spike (S) protein of SARS-CoV-2 harbors the receptor-binding domain (RBD) that mediates the virus's entry to host cells. The aim of this study was to identify novel inhibitors that target the RBD domain of S-protein through computational screening of chemical and natural compounds. Method: The S protein was modelled from the recently resolved and the previously described SARS-CoV protein structures. CLC Drug Discovery was used to computationally screen for potential inhibitory effects ofdoi:10.29117/quarfe.2020.0281 fatcat:s36ep42chjfsbdpsjuzkszdzxy