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A simple, solvent-free method was developed for preparation of fluorescent NSCPs by direct pyrolysis of gentamycin sulfate. The NSCPs showed high water-solubility, long lifetime, high quantum yield, excellent stability and low cytotoxicity, and thus can be used for cellular imaging.doi:10.1039/c4ra00012a fatcat:qv4tm4zncjeq5bctesn4bjzzzm