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Celiac disease is known as gluten enteropathy, caused by damaging of small intestinal epithelium cells following gluten consumption. Gluten is classified in two families of glutenin and gliadin. Gliadin is divided into α, γ and ω groups. One of the most effective methods to rectify or minimize gene expression is RNAi technology. The present study has been conducted to the structure of α-gliadin gene to produce proprietary RNAi cassette for silencing wheat α-gliadin gene. So nucleotide sequencedoi:10.4236/abb.2016.712047 fatcat:gvi4zmfsyzal5nt4i57p2mmvpe