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Melatonin for pre-medication in children: a systematic review
2022
BMC Pediatrics
Background Melatonin's effectiveness as an anxiolytic medication has been confirmed in adults; however, its efficacy in a paediatric population is unclear. A number of small studies have assessed its use in children as a pre-operative anxiolytic, with conflicting results. Methods We undertook a systematic review of pre-operative melatonin use in children. Four databases (MEDLINE, Embase, the Cochrane Central Register of Controlled Trials and Web of Science), and 'ClinicalTrials.gov' were
doi:10.1186/s12887-022-03149-w
pmid:35209863
pmcid:PMC8876113
fatcat:6ovnymoi7jhi5gxc4riidvkkvm