Specific and Rapid SARS-CoV-2 Identification Based on LC-MS/MS Analysis [post]

Ofir Schuster, Anat Zvi, Osnat Rosen, Hagit Achdout, Amir Ben-Shmuel, Ohad Shifman, Shmuel Yitzhaki, Orly Laskar, Liron Feldberg
2020 unpublished
This study describes the development of a novel assay for SARS-CoV-2 identification using LC-MS/MS analysis. A multi-step procedure for the rational down-selection of a set of markers has leaded to the discovery of six SARS-CoV-2 specific and sensitive markers, enabling the reliable identification of the virus. A rapid and simple assay was developed, successfully applied to clinical nasopharyngeal samples. The assay may potentially serve as a complementary approach for SARS-CoV-2 identification.
doi:10.26434/chemrxiv.13055873.v2 fatcat:ht3k5gfgjbbc5gmukq5w6vixq4