It has been established the new multifunctional metabolic bioformulations based on a set of biologically active substances from soil sreptomycetes Avercom, with the addition of elicitors of salicylic acid or chitosan, Violar and Phytovit promote the growth of microorganisms of major ecological and functional groups in the root area of spring wheat, and they increase the activity of the enzyme phenylanine- ammonia-lyase (PAL) in plant cells that indicates the induction of plant resistance to

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... ogens. This reduces the destruction of plants of spring wheat by the root rot and plant-parasitic nematodes. As a consequence of the action of Averсom nova-2, Violar and Phytovit the grain yield increased by 16.9–32.5% relative to control and 10.9–25.7% compared with chemical disinfectant Vitavaks 200 FF. At the same time the quality grain and proficiency were increased. The reduction of pesticide load on agrocenoses, an improvement of the ecological condition and the raise of productivity of agroecosystems can be achieved by using the new multifunctional metabolic bioformulations.