The role of inflammation on the functionality of intracortical microelectrodes

Janak Gaire, Heui Chang Lee, Nicholas Hilborn, Ray Ward, Mary Regan, Kevin J Otto
2018 Journal of Neural Engineering  
Neuroinflammation has long been associated with the performance decline of intracortical microelectrodes (IMEs). Consequently, several strategies, including the use of anti-inflammatories, have been employed to mitigate the inflammation surrounding IMEs. However, these strategies have had limited success towards achieving a chronically viable cortical neural interface, questioning the efficacy of anti-inflammatory approach.
doi:10.1088/1741-2552/aae4b6 pmid:30260321 fatcat:ttemfeawdndozdn3jc7wfaoela