Predictors of quality of life of patients with chronic obstructive pulmonary disease

Sladjana Vasiljevic, Marina Petrovic, Aleksandra Cvetkovic, Vesna Paunovic, Darko Mikic, Slavica Radjen
2017 Vojnosanitetski Pregled  
Background/Aim. Chronic obstructive pulmonary disease (COPD) has a significant impact on quality of life of patients. We investigated which demographic and social characteristics can predict the global quality of life (QoL) of COPD patients. Methods. The patients (n = 288) were divided into three groups according to the stage of disease: Group I = stage 0 -at risk; Group II = Stages I and II; Group III = stages III and IV. The patients fulfilled a questionnaire related to the demographic and
more » ... demographic and social characteristics and the validated multidimensional questionnaire -Serbian version of the St. George's Respiratory Questionnaire (SGRQ). The Student's t test, χ² test, ANOVA, univariate and multivariate logistic regression tests were used for statistical analyses. Results. In the group I, prevailed the men, employed persons, with a moderate financial status and no family history of COPD. In the group II dominated women, pensioners, with a moderate financial status, duration of illness up to five years, and no family history of COPD. In the group III prevailed women, unemployed persons, a moderate financial status, COPD duration up to 5 years and no family history of COPD. The predictors of the Symptoms score were grades of COPD and duration of the disease, and the predictors of Activity grades of COPD, sex, age and financial status. All variables were found to have a statistically significant relationship in the Impact score in the pre-analyses, were also significant in the univariate regression model. They were age, employement status, financial status and COPD duration. The same predictors that significantly contributed to the explanation of the Impact score, contributed to the explanation of the Total score on SGRQ. In the multivariate regression model, the predictors of the Activity score, Impacts score and Total score were the COPD grade and financial status; only the COPD grade contributed to the explanation of the Symptoms score. Conclusion. Financial status is the most important social factor, and the grade of COPD is the best disease-related predictor of QoL of COPD patients. Key words: pulmonary disease, chronic obstructive; quality of life; demography; socioeconomic factors; surveys and questionnaires; serbia. Apstrakt Uvod/Cilj. Hronična opstruktivna bolest pluća (HOBP) je progresivna i ireverzibilna bolest sa negativnim uticajem na kvalitet života obolelih. Cilj našeg ispitivanja bio je da odredi demografske i socijalne faktore obolelih koji su prediktori kvaliteta života. Metode. Bolesnici (n = 288) bili su podeljeni u tri grupe: I grupa -bolesnici u stadijumu 0 HOBP, u riziku; II grupa -bolesnici u stadijumu I i II HOBP; grupa III -bolesnici u stadijumu III i IV HOBP. Bolesnici su ispunjavali dva upitnika -jedan sa demografskim i socijalnim podacima, a drugi, validiranu srpsku verziju upitnika bolnice "Sveti Đorđe" o respiratornim teškoćama -St. George's Respiratory Questionnaire for Chronic Obstructive Pulmonary Disease (SGRQ-C). Podaci su obradjeni pomoću Student t-testa, χ² testa, ANOVA testa, kao i univariatnom i multivariatnom metodom logističke regresije. Rezultati. U grupi I dominirali su muškarci, zaposleni, osrednjeg materijalnog stanja, bez porodične anamneze HOBP. U grupi II je bilo više žena, penzionera, osrednjih prihoda, bolovanja do pet godina, bez HOBP u porodici. Žene, nezaposleni, osrednjih prihoda, trajanja HOBP do pet godina, bez HOBP u porodici, Vol. 76, No 7 VOJNOSANITETSKI PREGLED Page 717 Vasiljević S, et al. Vojnosanit Pregl 2019; 76(7): 716-722. dominirali su u III grupi. Prediktori za skor simptoma bili su stadijum bolesti i dužina bolovanja, dok su u skoru aktivnosti prediktori bili stadijum bolesti, pol, starost i finansijska situacija. Sve statistički značajne varijable u skoru uticaja u pre-analizama bile su značajne u univarijantnom regresionom modelu, a to su bili stadijum bolesti, starost, zaposlenje, finansijska situacija i dužina bolovanja. Isti prediktori objašnjavali su i ukupni skor u SGRQ. U multivarijantnom regresionom modelu, prediktori skora aktivnosti, skora uticaja i ukupnog skora bili su stadijum bolesti i finansijska si-tuacija; samo stadijum bolesti učestvovao je u objašnjenju skora simptoma. Zaključak. Finansijska situacija je najbolji socijalni prediktor, a stadijum bolesti najbolji od bolesti zavisan prediktor kvaliteta života obolelih od HOPB. Ključne reči: pluća, opstruktivne bolesti, hronične; kvalitet života; demografija; socijalno-ekonomski faktori; ankete i upitnici; srbija.
doi:10.2298/vsp161223147v fatcat:lgwafusbnbdnllpvphwe75dtym