Electrical induction hypothesis to explain enhancer-promoter communication [post]

Valentina Agoni
2015 unpublished
The steps of the DNA replication process remains to be clarified. Transcription factors are supposed to find their specific binding-sequence driven by epigenetic modifications and GpC islands. But then how can the replication machinery be able to find the promoters of exactly the genes that the cell needs to transcribe in that moment? Here we hypothesize a role of DNA conductance and electrical induction to give an explanation to this unsolved problem. Our hypothesis goes in accordance with the
more » ... accordance with the fact that many authors identified 3D loops in the genomes.
doi:10.7287/peerj.preprints.950 fatcat:3pr6jztxhzfv3nzzmnvzzbkuh4