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Under the ROS: Thiol network is the principal suspect for autophagy commitment
2010
Autophagy
and ciriolo@bio.uniroma2.it L ow molecular weight and protein sulphydryls undergo reactive oxygen species (ROS)-mediated oxidation. However, in contrast to the irreversible damages that oxidative conditions yield on biomolecules, the oxidation of reactive cysteines frequently results in reversible modifications, which represent the prototype of the molecular mechanisms underlying redox signaling. Many proteins involved in a wide range of cellular processes have been classified as
doi:10.4161/auto.6.7.12754
pmid:20639698
fatcat:7s2vnkf23ndofgnug4piiniuje