Nurse is a part of professional health care that provides nursing care to patient and family. Nurses must do their job quickly, precisely, and without mistakes. The high demand of nurse's job can lead mental workload. Mental workload that not managed properly will lead to burnout condition. This study aimed to analyze the effect of mental workload to the nurse's burnout level. This study was cross-sectional. The population was in-patient nurses in three private hospitals. The number of

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... nts was 89 nurses taken by proportionate stratified random sampling. The instruments were questionnaire of the mental workload from NASA-TLX and Maslach Burnout Inventory. Data were analyzed by ordinal regression test with p < 0.05. The effect of mental workload to the nurse's burnout level on the emotional exhaustion sub-scales was 0.001, depersonalization was 0.008, and personal accomplishment was 0.003. It concluded that there was an effect of mental workload to the nurse's burnout level. The high of mental workload could be due to high number of Bed Occupation Rate and total care level of dependence. The mental workload has an impact on the nurse's burnout on the three subscales. Keywords-mental workload, nurse, burnout level I. Data was analyzed by ordinal regression α≤0.05. Ethical concern on informed consent, anonymity, and confidentiality.