Building Biofoundry India: Challenges and Path Forward

Binay Panda, Pawan K Dhar
2021 Synthetic Biology  
Biofoundry is a place where biomanufacturing meets automation. The highly modular structure of a biofoundry helps accelerate the design-build-test-learn (DBTL) workflow to deliver products fast and in a streamlined fashion. In this perspective, we describe our efforts to build Biofoundry India (BI) and where we see the facility add substantial value in supporting research, innovation, and entrepreneurship. We describe three key areas of our focus, harnessing the potential of non-expressing
more » ... of the sequenced genomes, using deep learning in pathway reconstruction, and synthesis of enzymes and metabolites. Towards the end, we describe specific challenges in building such a facility in India and the path forward to mitigate some of those in working with the other biofoundries worldwide.
doi:10.1093/synbio/ysab015 pmid:34712840 pmcid:PMC8546612 fatcat:j5tj7wosrndotezhkbjknm6dju