Colon cancer is second leading cause of cancer death. Chemotherapy is considered an effective way to help cancer survivors but chemotherapy drugs are highly toxic and produce myelosuppression, hampers gastrointestinal tract and affects quality life of patients. It appears that side effects of chemotherapy are manifestations of aggravated Pittadosha as Raktapitta or Raktadushti (vitiated blood). Therefore, present case study was undertaken to find effectiveness of Ayurvedic medication in

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... ng the side effect of oral chemotherapy. A female patient of age 62 years with colon cancer undergoing oral chemotherapy by capecitabine 500 mg BD for 8 cycles of 14 days was taken. Patient was given classical ayurvedic formulation of Mauktikayukta Kamadudha 250mg + Pravalapanchamruta 250mg + Shuddhagairika 250mg + Mustadi Churṇa 1gram B.D., Suvarna Vasanta Malati 500mg B.D. with milk, Shatavari Ghrita 5ml B.D. and wheatgrass juice 10 ml at morning during total course of chemotherapy. After the completion of 8 th cycle there were very encouraging results observed with negligible side effects, no loss of hair and improvement in general h ealth condition of patient particularly weight which was only 35 kg is increases by 10 kg. Ayurvedic medication appears to have significant effect on reducing side effect of chemotherapy drug in colon cancer.