Efficacy of biocontrol agents and organic amendments was evaluated for their potential to manage the Fusarium wilt of tomato (Lycopersicon escluentum L.) caused by Fusarium oxysporum f. sp. lycopersici (FOL). Yeast, Trichoderma viride, T. harzianum and Pseudomonas spp. were collected from tomato growing areas of Tamil Nadu, India, and tested for antagonistic activity against the pathogen using a dual culture technique in Petri dishes. Yeast 1 was best in inhibiting mycelial growth of FOL

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... ), followed by Trichoderma viride 1 which inhibited mycelial growth by 68.50%. Among oil cakes and plant oil extracts tested, neem cake extract (5%) and neem oil (3%) reduced growth of FOL. The effective antagonists and organic amendments screened in vitro were confirmed in pot culture. In pot culture soil application of Yeast 1 @ 2.5 kg ha -1 was the most effective. Combinations screened in laboratory and pot culture conditions were tested against FOL under field conditions. The field experiment confirmed that Yeast 1 SA @ 2.5 kg ha -1 provided the best disease reduction over control and increased fruit yield.