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Aim. The article is devoted to the substantiation of theoretical and methodical principles of professional training of teachers of biology in the conditions of the informational and educational environment; multilevel and differentiated approaches in training with the possibility of continuous receipt of online and off-line assistance. Methods. Analysis of psychological and pedagogical, methodical literature; synthesis, a generalization; psycho-pedagogical observation, questionnaire,doi:10.7124/feeo.v25.1188 fatcat:rrzjvrxle5hmbpybm4car5l4ha