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Identity Other names: EC 22.214.171.124; JAK-1; JAK1A; JAK1B; JTK3 HGNC (Hugo): JAK1 Location: 1p31.3 DNA/RNA Description 25 exons spanning roughly 135 kb of genomic DNA. Transcription 5053 bp pre-mRNA; 1 transcript described. Protein Description 1154 amino acids; 133,3 kDa; JAK1 contains a Nterminal FERM domain, responsible of the binding to the receptor, a central Src homology 2 (SH2) domain, and two C-terminal domains: a tyrosine kinase domain JH1 and a pseudokinase domain JH2. Expressiondoi:10.4267/2042/44815 fatcat:fk6jwnpycjfgpfdx5huj2ipjiu