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Common genetic variants in the sex hormone-binding globulin (SHBG) gene in idiopathic recurrent pregnancy loss: a case control study
2018
Translational Medicine Communications
A role for sex hormone-binding globulin (SHBG) in determining the pregnancy outcome was evidenced by the rise in SHBG levels during pregnancy linked with favorable pregnancy, while reduction in SHBG levels and hyperandrogenemia were linked with poor pregnancy outcome. Since SHBG production is genetically determined, this study investigated the association of SHBG polymorphisms with the susceptibility to recurrent pregnancy loss (RPL). Methods: Retrospective case-control study, involving 308
doi:10.1186/s41231-018-0024-1
fatcat:qwlt3rs4enbbdf3uiuoouipsy4