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The paper studies ways of parallelization of hybrid immune algorithm of short-term forecasting of time series built on the basis of clonal selection model that uses case-based reasoning and the simplest methods of forecasting. There has been analysis performed of two variants of parallelization having different procedure of messaging between the computational nodes. To implement proposed algorithm used MPI.NET technology for messaging systems. To optimize individual computational nodesdoi:10.15588/1607-3274-2014-2-11 fatcat:z6qwdwk2bfghdimqk6gbg7qeji