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Objective: The objective of this work was to prepare and evaluate oral sustained release matrix tablet of highly water soluble drug and to study the effect of proportion of wax and addition of release liner on in-vitro release of drug. Method: The matrix tablets were prepared by melt granulation method using drug:wax in 1:1, 1:2 & 1:3 proportions and evaluated for on in-vitro drug release. Then the proportion 1:1 was selected and wax matrix tablets were prepared by three techniques meltdoi:10.22270/jddt.v4i3.868 fatcat:eixksrepvjg7njevci6qa4n6ly