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Large accelerator safety system design is complex and challenging. The complexity comes from the wide geographical distribution and the entangled control/protection functions that are shared across multiple control systems. To ensure safety performance and avoid unnecessary overdesign, a systematic approach should be followed when setting the functional requirements and the associated safety integrity. Layer of Protection Analysis (LOPA) is a method in IEC61511 for assigning the SIL to a safetydoi:10.18429/jacow-icalepcs2017-thcpa03 fatcat:4hwe653y2fbivd3werfidszxly