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In this work a new drug polymer was prepared from reaction of polyvinylpyrrolidone (PVP) with doxycylin in 10:1 dioxane: dimethelyformad solvent mixture. The prepared drug polymer was formed with 85% conversion percentage. The physical properties were studied and intrinsic viscosity was equal to 0.23 dl/g. The drug polymer was characterized by FT-IR and UV spectroscopy. The swelling % was studied in different non solvents. The elemental analysis and DSC were analyzed. The controlled releasefatcat:fdxyo2g5g5d7dg6ejqz437vgwq