Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes

Nura Suleiman Gwaram, Hapipah Mohd Ali, Hamid Khaledi, Mahmood Ameen Abdulla, A. Hamid A. Hadi, Thong Kwai Lin, Chai Lay Ching, Cher Lin Ooi
2012 Molecules  
A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities
more » ... ghest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa.
doi:10.3390/molecules17055952 pmid:22609786 fatcat:biw5ltuxozctxmvm32dcxi2axy