Nowadays, Oro dispersible tablets are gaining much importance because it is easily approachable and due to its patient compliance. In this study, Formulation and evaluation of one such tablets of Aceclofenac by direct compression method using super disintegrants like Cross carmellose sodium (CCS) was performed. Due to low water soluble property of aceclofenac, it has poor dissolution and bioavailability. In order to minimize this property OTD's are prepared. ODT's were prepared by direct

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... sion method using super disintegrant i.e Cross Carmellose Sodium (CCS) in different concentrations. The prepared powder blend was subjected to various evaluation studies like pre compression parameters like angle of repose, tapped density, and bulk density. Post compression parameters like weight variation, hardness, friability, drug content, wetting time, disintegration and dissolution studies were performed. The drug excipients compatibility was verified by FTIR. The precompression evaluation studies showed that the prepared powder blend has good flow property. The hardness and friability revealed that it has good mechanical strength with acceptable disintegration time. The optimized formulation indicated good in vitro drug dissolution profile with maximum drug being released at all the time intervals indicates an ideal profile for the development of ODT's. The results of pre compression studies and post compression along with FTIR are presented.