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Mast cell stabilizing activity of different extracts of Trigonella foenum-graecum was evaluated with the help of rat mesenteric mast cells. The study includes the mesenteries which are pretreated with prednisolone, petroleum ether, methanol and aqueous extract of Trigonella foenum-graecum (250mg, 500mg and 750mg) were analyzed for the degranulation of mast cell during the anaphylactic reactions. It was carried out on the mesenteries of rats, which are sensitized with sheep serum and tripledoi:10.6084/m9.figshare.1348748.v1 fatcat:rgf5rbfspbbidcmsoxe6g2vkne