ConStruct 1.0: An R Script to distinguish between substructure and consanguinity within a population using multilocus microsatellite data

Andrew D.J. Overall, Jurg Bahler
2016 Cogent Biology  
ConStruct.1.r is an R Script that estimates the relative contributions of consanguinity and population substructure to excess homozygosity. ConStruct.1.r also offers the option of simulating data with a given F ST and magnitude of consanguinity, incorporating a user-specified number of loci, number of alleles and population size. The method seems robust when population sizes are above 200 and individuals are genotyped at greater than 10 loci.
doi:10.1080/23312025.2015.1128317 fatcat:lopawk4mvjb6rcliluqxgjwqwy