A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf
.
DNA TOPOLOGY AND ADAPTATION OF SALMONELLA TYPHIMURIUM TO AN INTRACELLULAR ENVIRONMENT
2001
The Activities of Bacterial Pathogens In Vivo
The expression of genes coding for determinants of DNA topology in the facultative intracellular pathogen Salmonella typhimurium was studied during adaptation by the bacteria to the intracellular environment of J774A.1 macrophage-like cells. A reporter plasmid was used to monitor changes in DNA supercoiling during intracellular growth. Induction of the dps and spv genes, previously shown to be induced in the macrophage, was detected, as was expression of genes coding for DNA gyrase, integration
doi:10.1142/9781848161610_0002
fatcat:5dtqg4matvggnh3wbpmnzplw3e