Introduction and Aims: Vascular calcification (VC) is frequently observed in patients with chronic kidney disease (CKD). Numerous reports show that VC is an important risk factor for cardiovascular disease (CVD) events and mortality. It has also been known that calcium-based phosphate binders are more closely associated with the progression of VC than non-calcium-based phosphate binders. Lanthanum carbonate (LC) is one of the non-calcium-based phosphate binders that decreases serum phosphate

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... els in patients with CKD. Several studies have reported that LC has less effect on the progression of VC compared to that of calcium-based phosphate binders in the patients on maintenance haemodialysis (HD). Moreover, there are no reports on the effect on VC progression in CKD patients during the early period after the initiation of HD. In this study, we investigated the effect of LC on the progression of coronary artery calcification (CAC) compared to that of calcium-based phosphate binders in these patients.