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Rich-Club Connectivity of the Structural Covariance Network Relates to Memory Processes in Mild Cognitive Impairment and Alzheimer's Disease
2022
Journal of Alzheimer's Disease
Though mediotemporal lobe volume changes are well-known features of Alzheimer's disease (AD), grey matter volume changes may be distributed throughout the brain. These distributed changes are not independent due to the underlying network structure and can be described in terms of a structural covariance network (SCN). Objective: To investigate how the cortical brain organization is altered in AD we studied the mutual connectivity of hubs in the SCN, i.e., the rich-club. Methods: To construct
doi:10.3233/jad-220175
pmid:35871335
pmcid:PMC9484119
fatcat:6lysiacg2vdeth4fwkhtqvvpoi