The antimicrobial susceptibility profile of ESKAPE pathogens from urinary tract infections in a referral laboratory, Northeast Iran
Journal of Coastal Life Medicine
Objective: To assess the antimicrobial susceptibility pattern of ESKAPE pathogens from Neyshabur, Iran during 2013-2015. Methods: A total of 345 isolates including 62 Staphylococcus aureus (S. aureus), 38 Enterobacter spp. (including 14 Enterobacter agglomerans, 6 Enterobacter aerogenes and other 18 Enterobacter spp.), 123 Enterococcus faecium, 78 Klebsiella pneumonia, 10 Pseudomonas aeruginosa and 34 Acinetobacter baumannii were isolated. The antimicrobial susceptibility pattern of isolates
... tern of isolates was conducted with Kirby Bauer method. Data were analyzed with SPSS 20.0 software using F-and t-tests. Results: Among S. aureus isolates, the highest resistance was observed against nalidixic acid (81.35%) and cefixime (74.50%). Thirty-three (53.22%) S. aureus isolates were cefoxitin resistant (methicillin-resistant S. aureus). The majority of Enterobacter species was resistant to amikacin (100.00%) and cephalotin (66.60%). Most Enterococcus faecium isolates were resistant to nalidixic acid (89.43%) and amikacin (83.33%), but vancomycin-resistant enterococci isolates were not detected. Moreover, among Klebsiella pneumonia, the highest resistance was observed to nalidixic acid (20.98%) and cotrimoxazole (28.39%). Furthermore, all Pseudomonas aeruginosa isolates were resistant to cefotaxime (100.00%) and majority to nitroforantoin (88.80%). Acinetobacter baumannii isolates showed the highest and the lowest resistance to cefotaxime (100.00%) and cefixime (88.71%), respectively. Conclusions: The prevalence of ESKAPE pathogens from northeast region was low, but majority of them exhibited high rate of antibiotic resistance to common used antimicrobial agents.