The antimicrobial susceptibility profile of ESKAPE pathogens from urinary tract infections in a referral laboratory, Northeast Iran

2016 Journal of Coastal Life Medicine  
Objective: To assess the antimicrobial susceptibility pattern of ESKAPE pathogens from Neyshabur, Iran during 2013-2015. Methods: A total of 345 isolates including 62 Staphylococcus aureus (S. aureus), 38 Enterobacter spp. (including 14 Enterobacter agglomerans, 6 Enterobacter aerogenes and other 18 Enterobacter spp.), 123 Enterococcus faecium, 78 Klebsiella pneumonia, 10 Pseudomonas aeruginosa and 34 Acinetobacter baumannii were isolated. The antimicrobial susceptibility pattern of isolates
more » ... tern of isolates was conducted with Kirby Bauer method. Data were analyzed with SPSS 20.0 software using F-and t-tests. Results: Among S. aureus isolates, the highest resistance was observed against nalidixic acid (81.35%) and cefixime (74.50%). Thirty-three (53.22%) S. aureus isolates were cefoxitin resistant (methicillin-resistant S. aureus). The majority of Enterobacter species was resistant to amikacin (100.00%) and cephalotin (66.60%). Most Enterococcus faecium isolates were resistant to nalidixic acid (89.43%) and amikacin (83.33%), but vancomycin-resistant enterococci isolates were not detected. Moreover, among Klebsiella pneumonia, the highest resistance was observed to nalidixic acid (20.98%) and cotrimoxazole (28.39%). Furthermore, all Pseudomonas aeruginosa isolates were resistant to cefotaxime (100.00%) and majority to nitroforantoin (88.80%). Acinetobacter baumannii isolates showed the highest and the lowest resistance to cefotaxime (100.00%) and cefixime (88.71%), respectively. Conclusions: The prevalence of ESKAPE pathogens from northeast region was low, but majority of them exhibited high rate of antibiotic resistance to common used antimicrobial agents.
doi:10.12980/jclm.4.2016j6-194 fatcat:uhm2nj3zzbc77pi5cuhjabt72a