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The last steps of respiration, a core energy-harvesting process, are carried out by a chain of multi-subunit complexes in the inner mitochondrial membrane. Several essential subunits of the respiratory complexes are RNA-edited in plants, frequently leading to changes in the encoded amino acids. While the impact of RNA editing is clear at the sequence and phenotypic levels, the underlying biochemical explanations for these effects have remained obscure. Here, we used the structures of plantdoi:10.3390/ijms23020684 pmid:35054870 pmcid:PMC8775464 fatcat:r3boc3yeb5ca7hucpm6vazgj4u