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N-ferrocenylmethyl-Derivatives As Spike Glycoprotein Inhibitors Of SARS-CoV-2 Using In Silico Approaches
<p><b>Background and Objectives:</b> By the end of 2019, a novel human coronavirus outbreak started in Wuhan and spread to the world becoming a global pandemic, patients were diagnosed with severe respiratory syndrome. Studies have shown that SARS-CoV2 interact with angiotensin-converting enzyme 2 (ACE2), its host cell receptor, by its Spike Glycoprotein. The aim of this study is to prevent this interaction by inhibiting Spike glycoprotein.<b> Materials and Methods:</b> The interaction of thedoi:10.26434/chemrxiv.12278078.v1 fatcat:k7bbcoyn3zaktprrumvehrd7va