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BACKGROUND AND OBJECTIVES: Ankle sprain is one of the most frequent diseases in orthopedic emergencies. In general, analgesics and anti-inflammatory drugs are prescribed. This study aimed at evaluating whether 60 mg daily etoricoxib is as effective as 90 mg daily etoricoxib to treat pain and inflammation in patients with ankle sprain grades I and II. METHOD: This is a clinic, randomized, double-blind, prospective and controlled study which has evaluated 43 patients with ankle sprain grades Idoi:10.1590/s1806-00132012000200002 fatcat:fzvd67kd3razfkxs7cs5ngsd54