Phone number +66(2) 926-9794, Fax number +66(2) 926-9793 J o u r n a l P r e -p r o o f Abstract Cytomegalovirus (CMV) is one of the leading opportunistic pathogens affecting immunocompromised patients. We report a case of histologically-confirmed extensive CMV enterocolitis in a young woman after receiving rituximab and tocilizumab for the treatment of autoimmune encephalitis. During the antiviral treatment, she spontaneously excreted small intestinal casts per oral and colonic casts per anus.

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... Even though intestinal cast is an extremely unusual condition, CMV infection should be included in the differential diagnosis. J o u r n a l P r e -p r o o f Learning objectives We report a case of patient who developed small intestinal and colonic casts as a complication of extensive CMV enterocolitis following immunosuppressive therapy. Even though is finding is unusual, CMV infection should be included in the differential diagnosis of the passage of intestinal cast.