Incidence of SARS‐CoV‐2 infection among COVID‐19 vaccinated and unvaccinated healthcare personnel, first responders, and other essential and frontline workers: Eight US locations, January–September 2021

Allison L. Naleway, Lauren Grant, Alberto J. Caban‐Martinez, Meredith G. Wesley, Jefferey L. Burgess, Kimberly Groover, Manjusha Gaglani, Sarang K. Yoon, Harmony L. Tyner, Jennifer Meece, Jennifer L. Kuntz, Young M. Yoo (+36 others)
2022 Influenza and Other Respiratory Viruses  
We sought to evaluate the impact of changes in estimates of COVID-19 vaccine effectiveness on the incidence of laboratory-confirmed infection among frontline workers at high risk for SARS-CoV-2. Methods: We analyzed data from a prospective frontline worker cohort to estimate the incidence of COVID-19 by month as well as the association of COVID-19 vaccination, occupation, demographics, physical distancing, and mask use with infection risk. Participants completed baseline and quarterly surveys,
more » ... nd each week selfcollected mid-turbinate nasal swabs and reported symptoms. Results: Among 1018 unvaccinated and 3531 fully vaccinated workers, the monthly incidence of laboratory-confirmed SARS-CoV-2 infection in January 2021 was 13.9 (95% confidence interval [CI]: 10.4-17.4), declining to 0.5 (95% CI -0.4-1.4) per 1000 person-weeks in June. By September 2021, when the Delta variant predominated,
doi:10.1111/irv.12956 fatcat:fp5axh2cxzbk5kkhmcvciqsmym