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Slowing Down DNA Translocation through Solid-State Nanopores by Edge-Field Leakage
[post]
2020
unpublished
Solid-state nanopores allow high-throughput single-molecule detection but identifying and even registering all translocating small molecules remain key challenges due to their high translocation speeds. We show here the same electric field that drives the molecules into the pore can selectively pin and delay their transport. A thin high-permittivity dielectric coating on slender bullet-shaped polymer nanopores permits electric field leakage at the pore tip to produce a voltage-dependent surface
doi:10.21203/rs.3.rs-45233/v1
fatcat:aide2aztlfezzlrgnqoarddvdm