In this work we develop the path integral optimization in a class of inhomogeneous 2d CFTs constructed by putting an ordinary CFT on a space with a position dependent metric. After setting up and solving the general optimization problem, we study specific examples, including the Möbius, SSD and Rainbow deformed CFTs, and analyze path integral geometries and complexity for universal classes of states in these models. We find that metrics for optimal path integrals coincide with particular slices

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... of AdS3 geometries, on which Einstein's equations are equivalent to the condition for minimal path integral complexity. We also find that while leading divergences of path integral complexity remain unchanged, constant contributions are modified in a universal, position dependent manner. Moreover, we analyze entanglement entropies in inhomogeneous CFTs and show that they satisfy Hill's equations, which can be used to extract the energy density consistent with the first law of entanglement. Our findings not only support comparisons between slices of bulk spacetimes and circuits of path integrations, but also demonstrate that path integral geometries and complexity serve as a powerful tool for understanding the interesting physics of inhomogeneous systems.