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AbstractSeveral attempts have been made in order to isolate the effect of galaxy interactions by comparing galaxy in pairs with isolated galaxies. However, different authors have proposed different ways to build these control samples (CS). By using mock galaxy catalagues built up from the Millennium Simulation, we show that the set of constrains used to define a CS might introduce biases which could affect the interpretation of results. In this analysis, we make use of the fact that the physicsdoi:10.1017/s1743921310003467 fatcat:e6xarbzzqre4thxfvg3moucgdm