Attention deficit and hyperactivity disorder in people with epilepsy: diagnosis and implications to the treatment

Julio A.S. Koneski, Erasmo B. Casella
2010 Arquivos de Neuro-Psiquiatria  
The association between attention deficit and hyperactivity disorder (ADHD) and epilepsy can cause significant impact on the social life of affected individuals and their families. Clinical studies suggest that 30-40% of people with epilepsy also have ADHD. There are no studies which demonstrate that short or long-term treatment with methylphenidate increases the risk of seizures. Some studies attempt to relate drug interactions between methylphenidate and antiepileptic drugs, but adverse
more » ... , but adverse effects of methylphenidate have not been shown clearly. This review presents some neurobiological and physiopathogenic aspects, common to ADHD and epilepsy, from recent research studies, related to pharmacology, neuroimaging and electroencephalography. Possible risk of occurrence of seizures associated with the use of methylphenidate are also discussed.
doi:10.1590/s0004-282x2010000100023 pmid:20339664 fatcat:72on44pchnepvb34to5mt4e5zm