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Our aim was to study a role of nitrergic input in gastric relaxation in conscious dogs. Proximal gastric motor responses to mechanical distension and chemical stimulation (a lipid meal orally) were evaluated by electronic barostat. Effect of N G -monomethyl-Larginine acetate (L-NMMA, 5 mg/kg) on these responses was studied. When mechanical stimulation was applied, we observed steep linear increases in intragastric pressure up to about 6 mmHg, then continued to increase gradually, and could bedoi:10.1540/jsmr.40.53 pmid:15215633 fatcat:bnh6jqfy7vebnfxeqg657ndli4