A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
In this work, we report the preparation of a copper-silica material (Cu/SiO 2 ) by a sol-gel methodology and its characterization concerning composition and textural properties. The Cu/SiO 2 material was successfully applied as a Lewis acid heterogeneous catalyst for the A 3 -coupling from 2-aminopyridine, aldehydes and alkynes to imidazo[1,2-a]pyridines (45-82%), which are relevant pharmacological scaffolds. The synthesis shows a number of advantages, such as easy separation from the reactiondoi:10.21577/0103-5053.20190089 fatcat:jxt6amolj5bsjnptsszzx267zy